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Prediction of disulfide bond engineering sites using a machine learning method

Disulfide bonds are covalently bonded sulfur atoms from cysteine pairs in protein structures. Due to the importance of disulfide bonds in protein folding and structural stability, artificial disulfide bonds are often engineered by cysteine mutation to enhance protein structural stability. To facilit...

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Detalles Bibliográficos
Autores principales: Gao, Xiang, Dong, Xiaoqun, Li, Xuanxuan, Liu, Zhijie, Liu, Haiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316719/
https://www.ncbi.nlm.nih.gov/pubmed/32587353
http://dx.doi.org/10.1038/s41598-020-67230-z