Iron stored in ferritin is chemically reduced in the presence of aggregating Aβ(1-42)

Atypical low-oxidation-state iron phases in Alzheimer’s disease (AD) pathology are implicated in disease pathogenesis, as they may promote elevated redox activity and convey toxicity. However, the origin of low-oxidation-state iron and the pathways responsible for its formation and evolution remain...

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Detalles Bibliográficos
Autores principales: Everett, James, Brooks, Jake, Lermyte, Frederik, O’Connor, Peter B., Sadler, Peter J., Dobson, Jon, Collingwood, Joanna F., Telling, Neil D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316746/
https://www.ncbi.nlm.nih.gov/pubmed/32587293
http://dx.doi.org/10.1038/s41598-020-67117-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316746/
https://www.ncbi.nlm.nih.gov/pubmed/32587293
http://dx.doi.org/10.1038/s41598-020-67117-z

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