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Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions

Chronic musculoskeletal pain affects all aspects of human life. However, mechanisms of its genetic control remain poorly understood. Genetic studies of pain are complicated by the high complexity and heterogeneity of pain phenotypes. Here, we apply principal component analysis to reduce phenotype he...

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Detalles Bibliográficos
Autores principales: Tsepilov, Yakov A., Freidin, Maxim B., Shadrina, Alexandra S., Sharapov, Sodbo Z., Elgaeva, Elizaveta E., Zundert, Jan van, Karssen, Lennart С., Suri, Pradeep, Williams, Frances M. K., Aulchenko, Yurii S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316754/
https://www.ncbi.nlm.nih.gov/pubmed/32587327
http://dx.doi.org/10.1038/s42003-020-1051-9