Advances and potential pitfalls of oncolytic viruses expressing immunomodulatory transgene therapy for malignant gliomas

Glioblastoma (GBM) is an immunosuppressive, lethal brain tumor. Despite advances in molecular understanding and therapies, the clinical benefits have remained limited, and the life expectancy of patients with GBM has only been extended to ~15 months. Currently, genetically modified oncolytic viruses...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Liu, Fusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316762/
https://www.ncbi.nlm.nih.gov/pubmed/32587256
http://dx.doi.org/10.1038/s41419-020-2696-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316762/
https://www.ncbi.nlm.nih.gov/pubmed/32587256
http://dx.doi.org/10.1038/s41419-020-2696-5

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