Stabilization of HIF-1α alleviates osteoarthritis via enhancing mitophagy

Mitochondrial dysfunction leads to osteoarthritis (OA) and disc degeneration. Hypoxia inducible factor-1α (HIF-1α) mediated mitophagy has a protective role in several diseases. However, the underlying mechanism of HIF-1α mediated mitophagy in OA remains largely unknown. This current study was perfor...

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Detalles Bibliográficos
Autores principales: Hu, Sunli, Zhang, Chunwu, Ni, Libin, Huang, Chongan, Chen, Dingwen, Shi, Keqing, Jin, Haiming, Zhang, Kairui, Li, Yao, Xie, Ling, Fang, Mingqiao, Xiang, Guangheng, Wang, Xiangyang, Xiao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316774/
https://www.ncbi.nlm.nih.gov/pubmed/32587244
http://dx.doi.org/10.1038/s41419-020-2680-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316774/
https://www.ncbi.nlm.nih.gov/pubmed/32587244
http://dx.doi.org/10.1038/s41419-020-2680-0

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