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Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss

Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle beyond the inherent regenerative capacity of the body, generally leading to severe functional deficit. Formation of appropriate somato-motor innervations remains one of the biggest challenges for both autologous grafts...

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Detalles Bibliográficos
Autores principales: Das, Suradip, Browne, Kevin D., Laimo, Franco A., Maggiore, Joseph C., Hilman, Melanie C., Kaisaier, Halimulati, Aguilar, Carlos A., Ali, Zarina S., Mourkioti, Foteini, Cullen, D. Kacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316777/
https://www.ncbi.nlm.nih.gov/pubmed/32587337
http://dx.doi.org/10.1038/s42003-020-1056-4