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Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss
Volumetric muscle loss (VML) is the traumatic or surgical loss of skeletal muscle beyond the inherent regenerative capacity of the body, generally leading to severe functional deficit. Formation of appropriate somato-motor innervations remains one of the biggest challenges for both autologous grafts...
Autores principales: | Das, Suradip, Browne, Kevin D., Laimo, Franco A., Maggiore, Joseph C., Hilman, Melanie C., Kaisaier, Halimulati, Aguilar, Carlos A., Ali, Zarina S., Mourkioti, Foteini, Cullen, D. Kacy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316777/ https://www.ncbi.nlm.nih.gov/pubmed/32587337 http://dx.doi.org/10.1038/s42003-020-1056-4 |
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