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Ursodeoxycholic acid improves feto-placental and offspring metabolic outcomes in hypercholanemic pregnancy

Perturbations in the intrauterine environment can result in lifelong consequences for metabolic health during postnatal life. Intrahepatic cholestasis of pregnancy (ICP) can predispose offspring to metabolic disease in adulthood, likely due to a combination of the effects of increased bile acids, ma...

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Detalles Bibliográficos
Autores principales: Borges Manna, Luiza, Papacleovoulou, Georgia, Flaviani, Flavia, Pataia, Vanessa, Qadri, Asaad, Abu-Hayyeh, Shadi, McIlvride, Saraid, Jansen, Eugene, Dixon, Peter, Chambers, Jennifer, Vazquez-Lopez, Marta, Wahlström, Annika, Kitaba, Negusse, Marschall, Hanns-Ulrich, Godfrey, Keith M., Lillycrop, Karen, Williamson, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316783/
https://www.ncbi.nlm.nih.gov/pubmed/32587408
http://dx.doi.org/10.1038/s41598-020-67301-1