Cargando…

Ursodeoxycholic acid improves feto-placental and offspring metabolic outcomes in hypercholanemic pregnancy

Perturbations in the intrauterine environment can result in lifelong consequences for metabolic health during postnatal life. Intrahepatic cholestasis of pregnancy (ICP) can predispose offspring to metabolic disease in adulthood, likely due to a combination of the effects of increased bile acids, ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borges Manna, Luiza, Papacleovoulou, Georgia, Flaviani, Flavia, Pataia, Vanessa, Qadri, Asaad, Abu-Hayyeh, Shadi, McIlvride, Saraid, Jansen, Eugene, Dixon, Peter, Chambers, Jennifer, Vazquez-Lopez, Marta, Wahlström, Annika, Kitaba, Negusse, Marschall, Hanns-Ulrich, Godfrey, Keith M., Lillycrop, Karen, Williamson, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316783/ https://www.ncbi.nlm.nih.gov/pubmed/32587408 http://dx.doi.org/10.1038/s41598-020-67301-1

Ejemplares similares

A progesterone-brown fat axis is involved in regulating fetal growth
por: McIlvride, Saraid, et al.
Publicado: (2017)

Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia
por: Pataia, Vanessa, et al.
Publicado: (2020)

The Reversed Feto-Maternal Bile Acid Gradient in Intrahepatic Cholestasis of Pregnancy Is Corrected by Ursodeoxycholic Acid
por: Geenes, Victoria, et al.
Publicado: (2014)

Maternal glucose homeostasis is impaired in mouse models of gestational cholestasis
por: Bellafante, Elena, et al.
Publicado: (2020)

Paternal cholestasis exacerbates obesity-associated hypertension in male offspring but is prevented by paternal ursodeoxycholic acid treatment
por: Pataia, Vanessa, et al.
Publicado: (2018)

Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in mouse model of gestational diabetes
por: McIlvride, Saraid, et al.
Publicado: (2019)

Feto-Maternal Effects of Adding Rifampicin to Ursodeoxycholic Acid in the Treatment of Intrahepatic Cholestasis of Pregnancy
por: Kumari, Anjali, et al.
Publicado: (2022)

Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5
por: Ibrahim, Effendi, et al.
Publicado: (2018)

Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy
por: Ovadia, Caroline, et al.
Publicado: (2020)

Intrahepatic Cholestasis of Pregnancy Levels of Sulfated Progesterone Metabolites Inhibit Farnesoid X Receptor Resulting in a Cholestatic Phenotype
por: Abu-Hayyeh, Shadi, et al.
Publicado: (2013)

Changes in LXR signaling influence early-pregnancy lipogenesis and protect against dysregulated fetoplacental lipid homeostasis
por: Nikolova, Vanya, et al.
Publicado: (2017)

Ursodeoxycholic acid: Effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients
por: Mueller, Michaela, et al.
Publicado: (2017)

Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study
por: Manna, LB, et al.
Publicado: (2019)

Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity
por: Mueller, Michaela, et al.
Publicado: (2015)

Fat Malabsorption and Ursodeoxycholic Acid Treatment in Children With Reduced Organic Solute Transporter-α (SLC51A) Expression
por: Tronstad, Rune Rose, et al.
Publicado: (2022)

La Reproducción y el feto /
por: Findlay, Alan L. R.
Publicado: (1987)

Sulfated Progesterone Metabolites That Enhance Insulin Secretion via TRPM3 Are Reduced in Serum From Women With Gestational Diabetes Mellitus
por: Fan, Hei Man, et al.
Publicado: (2022)

Feto-maternal biology and ethics of human society
por: Paulesu, Luana, et al.
Publicado: (2005)

Feto-Maternal Microchimerism: The Pre-eclampsia Conundrum
por: Hahn, Sinuhe, et al.
Publicado: (2019)

Feto-maternal microchimerism: Memories from pregnancy
por: Cómitre-Mariano, Blanca, et al.
Publicado: (2021)

Pregnancy Complications and Feto-Maternal Monitoring in Rabbits
por: Pinto-Pinho, Patrícia, et al.
Publicado: (2023)

Influence of Maternal Lifestyle and Diet on Perinatal DNA Methylation Signatures Associated With Childhood Arterial Stiffness at 8 to 9 Years
por: Murray, Robert, et al.
Publicado: (2021)

A multi-centered trial investigating gestational treatment with ursodeoxycholic acid compared to metformin to reduce effects of diabetes mellitus (GUARD): a randomized controlled trial protocol
por: Lovell, Holly, et al.
Publicado: (2022)

Biological synthesis of ursodeoxycholic acid
por: Song, Peng, et al.
Publicado: (2023)

Development of a New Patient-reported Outcome Instrument to Evaluate Treatments for Scars: The SCAR-Q
por: Klassen, Anne F., et al.
Publicado: (2018)

"Agresión farmacológica y ambiental sobre el feto" /
por: Rolón Ochoa, Reyna Myrna
Publicado: (1992)

Feto-Maternal Trafficking of Exosomes in Murine Pregnancy Models
por: Sheller-Miller, Samantha, et al.
Publicado: (2016)

Extracellular Vesicles in Feto–Maternal Crosstalk and Pregnancy Disorders
por: Buca, Danilo, et al.
Publicado: (2020)

Sphingolipid Signature of Human Feto-Placental Vasculature in Preeclampsia
por: Del Gaudio, Ilaria, et al.
Publicado: (2020)

Feto-Maternal Crosstalk in the Development of the Circadian Clock System
por: Astiz, Mariana, et al.
Publicado: (2021)

Effect of Ursodeoxycholic Acid Alone and Ursodeoxycholic Acid Plus Domperidone on Radiolucent Gallstones and Gallbladder Contractility in Humans
por: Tuncer, Ilyas, et al.
Publicado: (2012)

Cyp3a11 is not essential for the formation of murine bile acids
por: Wahlström, Annika, et al.
Publicado: (2017)

Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis
por: Gurung, Vinita, et al.
Publicado: (2009)

Maternal dysglycaemia, changes in the infant’s epigenome modified with a diet and physical activity intervention in pregnancy: Secondary analysis of a randomised control trial
por: Antoun, Elie, et al.
Publicado: (2020)

The Conservative Management of Choledocholithiasis With Ursodeoxycholic Acid
por: Oluboyede, Daniel O, et al.
Publicado: (2023)

Molecular Mechanisms of Ursodeoxycholic Acid Toxicity & Side Effects: Ursodeoxycholic Acid Freezes Regeneration & Induces Hibernation Mode
por: Kotb, Magd A.
Publicado: (2012)

Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a secondary analysis of the PITCHES trial
por: Fleminger, J, et al.
Publicado: (2020)

Organ-On-Chip Technology: The Future of Feto-Maternal Interface Research?
por: Richardson, Lauren, et al.
Publicado: (2020)

Ursodeoxycholic acid production by Gibberella zeae mutants
por: Kollerov, Vyacheslav, et al.
Publicado: (2022)

Behrman, enfermedades del feto y del recién nacido : perinatología-neonatología
Publicado: (1986)

Cannot write session to /tmp/vufind_sessions/sess_n8e809fgnaqe8bf66p06jmhe77