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Lysophosphatidylcholine acyltransferase 2 (LPCAT2) co-localises with TLR4 and regulates macrophage inflammatory gene expression in response to LPS

Despite extensive investigations, an effective treatment for sepsis remains elusive and a better understanding of the inflammatory response to infection is required to identify potential new targets for therapy. In this study we have used RNAi technology to show, for the first time, that the inducib...

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Detalles Bibliográficos
Autores principales: Abate, W., Alrammah, H., Kiernan, M., Tonks, A. J., Jackson, S. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316826/
https://www.ncbi.nlm.nih.gov/pubmed/32587324
http://dx.doi.org/10.1038/s41598-020-67000-x