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Lysophosphatidylcholine acyltransferase 2 (LPCAT2) co-localises with TLR4 and regulates macrophage inflammatory gene expression in response to LPS
Despite extensive investigations, an effective treatment for sepsis remains elusive and a better understanding of the inflammatory response to infection is required to identify potential new targets for therapy. In this study we have used RNAi technology to show, for the first time, that the inducib...
Autores principales: | Abate, W., Alrammah, H., Kiernan, M., Tonks, A. J., Jackson, S. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316826/ https://www.ncbi.nlm.nih.gov/pubmed/32587324 http://dx.doi.org/10.1038/s41598-020-67000-x |
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