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Efficacy of oral administration of cystine and theanine in colorectal cancer patients undergoing capecitabine-based adjuvant chemotherapy after surgery: a multi-institutional, randomized, double-blinded, placebo-controlled, phase II trial (JORTC-CAM03)

PURPOSE: Capecitabine-based adjuvant chemotherapy for colorectal cancer patients often causes adverse events (AEs), such as diarrhea, stomatitis, anorexia, and hand-foot syndrome (HFS). Cystine and theanine were reported to attenuate some chemotherapy-associated AEs, and hence are also expected to a...

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Detalles Bibliográficos
Autores principales: Hamaguchi, Reo, Tsuchiya, Takashi, Miyata, Go, Sato, Toshihiko, Takahashi, Kenichi, Miura, Koh, Oshio, Hiroshi, Ohori, Hisatsugu, Ariyoshi, Keisuke, Oyamada, Shunsuke, Iwase, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316838/
https://www.ncbi.nlm.nih.gov/pubmed/31811480
http://dx.doi.org/10.1007/s00520-019-05205-1