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Engineering intracellular malonyl-CoA availability in microbial hosts and its impact on polyketide and fatty acid synthesis
Malonyl-CoA is an important central metabolite serving as the basic building block for the microbial synthesis of many pharmaceutically interesting polyketides, but also fatty acid–derived compounds including biofuels. Especially Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutam...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316851/ https://www.ncbi.nlm.nih.gov/pubmed/32385515 http://dx.doi.org/10.1007/s00253-020-10643-7 |