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Identification of a Compound That Inhibits the Growth of Gram-Negative Bacteria by Blocking BamA–BamD Interaction

The demand for novel antibiotics is imperative for drug-resistant Gram-negative bacteria which causes diverse intractable infection disease in clinic. Here, a comprehensive screening was implemented to identify potential agents that disrupt the assembly of β-barrel outer-membrane proteins (OMPs) in...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhu, Xiaohong, Zhang, Jing, Lin, Yuan, You, Xuefu, Chen, Minghua, Wang, Yanchang, Zhu, Ningyu, Si, Shuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316895/
https://www.ncbi.nlm.nih.gov/pubmed/32636816
http://dx.doi.org/10.3389/fmicb.2020.01252