The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer

Long intergenic non-coding RNA-Nucleotide Metabolism Regulator (lincNMR) is a long non-coding RNA (lncRNA) which is induced in hepatocellular carcinoma. Its depletion invokes a proliferation defect, triggers senescence and inhibits colony formation in liver, but also breast and lung cancer cells. Tr...

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Detalles Bibliográficos
Autores principales: Gandhi, Minakshi, Groß, Matthias, Holler, Jessica M., Coggins, Si’Ana A., Patil, Nitin, Leupold, Joerg H., Munschauer, Mathias, Schenone, Monica, Hartigan, Christina R., Allgayer, Heike, Kim, Baek, Diederichs, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316977/
https://www.ncbi.nlm.nih.gov/pubmed/32587247
http://dx.doi.org/10.1038/s41467-020-17007-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316977/
https://www.ncbi.nlm.nih.gov/pubmed/32587247
http://dx.doi.org/10.1038/s41467-020-17007-9

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