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The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer
Long intergenic non-coding RNA-Nucleotide Metabolism Regulator (lincNMR) is a long non-coding RNA (lncRNA) which is induced in hepatocellular carcinoma. Its depletion invokes a proliferation defect, triggers senescence and inhibits colony formation in liver, but also breast and lung cancer cells. Tr...
Autores principales: | Gandhi, Minakshi, Groß, Matthias, Holler, Jessica M., Coggins, Si’Ana A., Patil, Nitin, Leupold, Joerg H., Munschauer, Mathias, Schenone, Monica, Hartigan, Christina R., Allgayer, Heike, Kim, Baek, Diederichs, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316977/ https://www.ncbi.nlm.nih.gov/pubmed/32587247 http://dx.doi.org/10.1038/s41467-020-17007-9 |
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