PPARγ as an E3 Ubiquitin-Ligase Impedes Phosphate-Stat6 Stability and Promotes Prostaglandins E(2)-Mediated Inhibition of IgE Production in Asthma

Increased serum IgE level is one of the features of allergic asthma. It is reported that IgE production can be enhanced by E-prostanoid 2 (EP2) receptor of prostaglandin E(2) (PGE(2)); however, whether E-prostanoid 4 (EP4) receptor (encoded by Ptger4) has a unique or redundant role is still unclear....

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Detalles Bibliográficos
Autores principales: Wu, Jia, Wang, Yan, Zhou, Yu, Wang, Yuqing, Sun, Xiaowan, Zhao, Ye, Guan, Youfei, Zhang, Yu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317005/
https://www.ncbi.nlm.nih.gov/pubmed/32636842
http://dx.doi.org/10.3389/fimmu.2020.01224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317005/
https://www.ncbi.nlm.nih.gov/pubmed/32636842
http://dx.doi.org/10.3389/fimmu.2020.01224

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