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Oxymatrine Inhibits Twist-Mediated Renal Tubulointerstitial Fibrosis by Upregulating Id2 Expression

The final pathway for the development of diabetic nephropathy (DN) into chronic renal failure in DN is glomerulosclerosis and tubulointerstitial fibrosis. Renal tubular lesions can occur in the early stage of DN renal injury. Cumulative evidence shows that oxymatrine (OMT) has a variety of biologica...

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Detalles Bibliográficos
Autores principales: Xiao, Ying, Peng, Can, Xiao, Yawen, Liang, Dan, Yuan, Zhiping, Li, Zhiyang, Shi, Mingjun, Wang, Yuanyuan, Zhang, Fan, Guo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317027/
https://www.ncbi.nlm.nih.gov/pubmed/32636757
http://dx.doi.org/10.3389/fphys.2020.00599