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Genetics of human malignant peripheral nerve sheath tumors

Malignant peripheral nerve sheath tumors (MPNSTs) are heterogeneous, highly aggressive tumors with no widely effective treatment other than surgery. Genomic architecture of MPNST is similar to other soft tissue sarcomas, with a relatively modest burden of single nucleotide variants and an elevated f...

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Detalles Bibliográficos
Autores principales: Pemov, Alexander, Li, Hua, Presley, William, Wallace, Margaret R, Miller, David T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317054/
https://www.ncbi.nlm.nih.gov/pubmed/32642732
http://dx.doi.org/10.1093/noajnl/vdz049