After Nf1 loss in Schwann cells, inflammation drives neurofibroma formation

Plexiform neurofibromas (PNF) are peripheral nerve tumors caused by bi-allelic loss of NF1 in the Schwann cell (SC) lineage. PNF are common in individuals with Neurofibromatosis type I (NF1) and can cause significant patient morbidity, spurring research into potential therapies. Immune cells are rar...

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Detalles Bibliográficos
Autores principales: Fletcher, Jonathan S, Pundavela, Jay, Ratner, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Supplement Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317060/
https://www.ncbi.nlm.nih.gov/pubmed/32642730
http://dx.doi.org/10.1093/noajnl/vdz045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317060/
https://www.ncbi.nlm.nih.gov/pubmed/32642730
http://dx.doi.org/10.1093/noajnl/vdz045

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