Whole exome sequencing reveals the maintained polyclonal nature from primary to metastatic malignant peripheral nerve sheath tumor in two patients with NF1

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas with high metastatic rates and poor overall patient survival. There are currently no effective therapies, underscoring the pressing need to define the molecular etiologies that underlie MPNST progressio...

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Detalles Bibliográficos
Autores principales: Godec, Abigail, Jayasinghe, Reyka, Chrisinger, John S A, Prudner, Bethany, Ball, Tyler, Wang, Yuxi, Srihari, Divya, Kaushal, Madhurima, Dietz, Hilary, Zhang, Xiaochun, Pekmezci, Melike, Dahiya, Sonika, Tao, Yu, Luo, Jinqin, Van Tine, Brian A, Ding, Li, Gutmann, David H, Hirbe, Angela C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Supplement Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317063/
https://www.ncbi.nlm.nih.gov/pubmed/32642734
http://dx.doi.org/10.1093/noajnl/vdz026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317063/
https://www.ncbi.nlm.nih.gov/pubmed/32642734
http://dx.doi.org/10.1093/noajnl/vdz026

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