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Mathematical modeling of the ‘inoculum effect': six applicable models and the MIC advancement point concept

Antimicrobial treatment regimens against bacterial pathogens are designed using the drug's minimum inhibitory concentration (MIC) measured at a bacterial density of 5.7 log(10)(colony-forming units (CFU)/mL) in vitro. However, MIC changes with pathogen density, which varies among infectious dis...

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Detalles Bibliográficos
Autores principales: Salas, Jessica R, Jaberi-Douraki, Majid, Wen, Xuesong, Volkova, Victoriya V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317156/
https://www.ncbi.nlm.nih.gov/pubmed/31960902
http://dx.doi.org/10.1093/femsle/fnaa012