Gardenia jasminoides extract and its constituent, genipin, inhibit activation of CD3/CD28 co-stimulated CD4(+) T cells via ORAI1 channel

Gardenia jasminoides (GJ) is a widely used herbal medicine with anti-inflammatory properties, but its effects on the ORAI1 channel, which is important in generating intracellular calcium signaling for T cell activation, remain unknown. In this study, we investigated whether 70% ethanolic GJ extract...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Jong, Nam, Yu Ran, Woo, JooHan, Kim, Woo Kyung, Nam, Joo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317176/
https://www.ncbi.nlm.nih.gov/pubmed/32587130
http://dx.doi.org/10.4196/kjpp.2020.24.4.363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317176/
https://www.ncbi.nlm.nih.gov/pubmed/32587130
http://dx.doi.org/10.4196/kjpp.2020.24.4.363

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