Cargando…

Exploring the beneficial role of telmisartan in sepsis-induced myocardial injury through inhibition of high-mobility group box 1 and glycogen synthase kinase-3β/nuclear factor-κB pathway

In the present experimental study, cecal ligation and puncture significantly increased the myocardial injury assessed in terms of excess release of creative kinase-MB (CK-MB), cardiac troponin I (cTnI), interleukin (IL)-6 and decrease of IL-10 in the blood following 12 h of laparotomy procedure as c...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Yan, Wang, Hong, Li, Jing, Dang, Minyan, Zhang, Wenzhi, Lei, Yan, Zhao, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317178/
https://www.ncbi.nlm.nih.gov/pubmed/32587125
http://dx.doi.org/10.4196/kjpp.2020.24.4.311