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Luteolin reduces fluid hypersecretion by inhibiting TMEM16A in interleukin-4 treated Calu-3 airway epithelial cells

Rhinorrhea in allergic rhinitis (AR) is characterized by the secretion of electrolytes in the nasal discharge. The secretion of Cl(–) and HCO(3)(–) is mainly regulated by cystic fibrosis transmembrane conductance regulator (CFTR) or via the calcium-activated Cl(–) channel anoctamin-1 (ANO1) in nasal...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Jong, Woo, JooHan, Nam, Yu-Ran, Seo, Yohan, Namkung, Wan, Nam, Joo Hyun, Kim, Woo Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317179/
https://www.ncbi.nlm.nih.gov/pubmed/32587127
http://dx.doi.org/10.4196/kjpp.2020.24.4.329