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Protein Delivery of Cell-Penetrating Zinc-Finger Activators Stimulates Latent HIV-1-Infected Cells

Despite efforts to develop effective treatments for eradicating HIV-1, a cure has not yet been achieved. Whereas antiretroviral drugs target an actively replicating virus, latent, nonreplicative forms persist during treatment. Pharmacological strategies that reactivate latent HIV-1 and expose cellul...

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Detalles Bibliográficos
Autores principales: Perdigão, Pedro R.L., Cunha-Santos, Catarina, Barbas, Carlos F., Santa-Marta, Mariana, Goncalves, Joao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317221/
https://www.ncbi.nlm.nih.gov/pubmed/32637446
http://dx.doi.org/10.1016/j.omtm.2020.05.016