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Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies.

BACKGROUND: Subcellular localization and function of L-type calcium channels (LTCCs) play an important role in regulating contraction of cardiomyocytes. Understanding how this is affected by the disruption of transverse tubules during heart failure could lead to new insights into the disease. METHOD...

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Detalles Bibliográficos
Autores principales: Sanchez-Alonso, Jose L., Loucks, Alexandra, Schobesberger, Sophie, van Cromvoirt, Ankie M., Poulet, Claire, Chowdhury, Rasheda A., Trayanova, Natalia, Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317229/
https://www.ncbi.nlm.nih.gov/pubmed/32580140
http://dx.doi.org/10.1016/j.ebiom.2020.102845