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Interleukin-22 Inhibits Respiratory Syncytial Virus Production by Blocking Virus-Mediated Subversion of Cellular Autophagy

Respiratory syncytial virus (RSV) infection can cause severe bronchiolitis in infants requiring hospitalization, whereas the elderly and immunocompromised are prone to RSV-induced pneumonia. RSV primarily infects lung epithelial cells. Given that no vaccine against RSV is currently available, we tes...

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Detalles Bibliográficos
Autores principales: Das, Sudipta, St. Croix, Claudette, Good, Misty, Chen, Jie, Zhao, Jinming, Hu, Sanmei, Ross, Mark, Myerburg, Michael M., Pilewski, Joseph M., Williams, John, Wenzel, Sally E., Kolls, Jay K., Ray, Anuradha, Ray, Prabir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317237/
https://www.ncbi.nlm.nih.gov/pubmed/32580124
http://dx.doi.org/10.1016/j.isci.2020.101256