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Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery

BACKGROUND: Many flaviviruses are significant human pathogens that cause global public health threats. Developing research tools for studying and diagnosing these pathogens is a top priority. Reporter flaviviruses are useful tools for studying viral pathogenesis, diagnosing disease, and screening an...

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Detalles Bibliográficos
Autores principales: Baker, Coleman, Xie, Xuping, Zou, Jing, Muruato, Antonio, Fink, Katja, Shi, Pei-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317239/
https://www.ncbi.nlm.nih.gov/pubmed/32574959
http://dx.doi.org/10.1016/j.ebiom.2020.102838