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Development of small‐scale models to understand the impact of continuous downstream bioprocessing on integrated virus filtration
We designed small‐scale virus filtration models to investigate the impact of the extended process times and dynamic product streams present in continuous manufacturing. Our data show that the Planova 20N and BioEX virus filters are capable of effectively removing bacteriophage PP7 (>4 log) when r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317339/ https://www.ncbi.nlm.nih.gov/pubmed/31945257 http://dx.doi.org/10.1002/btpr.2962 |