Cargando…

Development of small‐scale models to understand the impact of continuous downstream bioprocessing on integrated virus filtration

We designed small‐scale virus filtration models to investigate the impact of the extended process times and dynamic product streams present in continuous manufacturing. Our data show that the Planova 20N and BioEX virus filters are capable of effectively removing bacteriophage PP7 (>4 log) when r...

Descripción completa

Detalles Bibliográficos
Autores principales: Lute, Scott, Kozaili, Julie, Johnson, Sarah, Kobayashi, Kazuya, Strauss, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317339/
https://www.ncbi.nlm.nih.gov/pubmed/31945257
http://dx.doi.org/10.1002/btpr.2962