Peptidylarginine Deiminase Autoimmunity and the Development of Anti–Citrullinated Protein Antibody in Rheumatoid Arthritis: The Hapten–Carrier Model

OBJECTIVE: The presence of autoantibodies to citrullinated proteins (ACPAs) often precedes the development of rheumatoid arthritis (RA). Citrullines are arginine residues that have been modified by peptidylarginine deiminases (PADs). PAD4 is the target of autoantibodies in RA. ACPAs could arise beca...

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Detalles Bibliográficos
Autores principales: Auger, Isabelle, Balandraud, Nathalie, Massy, Emmanuel, Hemon, Marie F., Peen, Elisa, Arnoux, Fanny, Mariot, Charlotte, Martin, Marielle, Lafforgue, Pierre, Busnel, Jean‐Marc, Roudier, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Rheumatoid Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317357/
https://www.ncbi.nlm.nih.gov/pubmed/31820586
http://dx.doi.org/10.1002/art.41189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317357/
https://www.ncbi.nlm.nih.gov/pubmed/31820586
http://dx.doi.org/10.1002/art.41189

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