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Development and validation of a multiplex UHPLC‐MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV

The widespread use of highly active antiretroviral treatments has dramatically changed the prognosis of people living with HIV (PLWH). However, such treatments have to be taken lifelong raising issues regarding the maintenance of both therapeutic effectiveness and long‐term tolerability. Recently ap...

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Detalles Bibliográficos
Autores principales: Courlet, Perrine, Alves Saldanha, Susana, Cavassini, Matthias, Marzolini, Catia, Choong, Eva, Csajka, Chantal, Günthard, Huldrych F., André, Pascal, Buclin, Thierry, Desfontaine, Vincent, Decosterd, Laurent Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317362/
https://www.ncbi.nlm.nih.gov/pubmed/32160389
http://dx.doi.org/10.1002/jms.4506