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Using Machine Learning Methods and Structural Alerts for Prediction of Mitochondrial Toxicity

Over the last few years more and more organ and idiosyncratic toxicities were linked to mitochondrial toxicity. Despite well‐established assays, such as the seahorse and Glucose/Galactose assay, an in silico approach to mitochondrial toxicity is still feasible, particularly when it comes to the asse...

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Detalles Bibliográficos
Autores principales: Hemmerich, Jennifer, Troger, Florentina, Füzi, Barbara, F.Ecker, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317375/
https://www.ncbi.nlm.nih.gov/pubmed/32108997
http://dx.doi.org/10.1002/minf.202000005