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Germ‐free and microbiota‐associated mice yield small intestinal epithelial organoids with equivalent and robust transcriptome/proteome expression phenotypes

Intestinal epithelial organoids established from gut tissue have become a widely used research tool. However, it remains unclear how environmental cues, divergent microbiota composition and other sources of variation before, during and after establishment confound organoid properties, and how these...

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Detalles Bibliográficos
Autores principales: Hausmann, Annika, Russo, Giancarlo, Grossmann, Jonas, Zünd, Mirjam, Schwank, Gerald, Aebersold, Ruedi, Liu, Yansheng, Sellin, Mikael E., Hardt, Wolf‐Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317401/
https://www.ncbi.nlm.nih.gov/pubmed/32068945
http://dx.doi.org/10.1111/cmi.13191