Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach

Pharmacophore searches that include anchors, fragments contributing above average to receptor binding, combined with one‐step syntheses are a powerful approach for the fast discovery of novel bioactive molecules. Here, we are presenting a pipeline for the rapid and efficient discovery of aspartyl pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Konstantinidou, Markella, Magari, Francesca, Sutanto, Fandi, Haupenthal, Jörg, Jumde, Varsha R., Ünver, M. Yagiz, Heine, Andreas, Camacho, Carlos Jamie, Hirsch, Anna K. H., Klebe, Gerhard, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317454/
https://www.ncbi.nlm.nih.gov/pubmed/32187447
http://dx.doi.org/10.1002/cmdc.202000024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317454/
https://www.ncbi.nlm.nih.gov/pubmed/32187447
http://dx.doi.org/10.1002/cmdc.202000024

Ejemplares similares