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Probiotic Lactobacillus rhamnosus GG Prevents Liver Fibrosis Through Inhibiting Hepatic Bile Acid Synthesis and Enhancing Bile Acid Excretion in Mice

BACKGROUND AND AIMS: Cholestatic liver disease is characterized by gut dysbiosis and excessive toxic hepatic bile acids (BAs). Modification of gut microbiota and repression of BA synthesis are potential strategies for the treatment of cholestatic liver disease. The purpose of this study was to exami...

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Detalles Bibliográficos
Autores principales: Liu, Yunhuan, Chen, Kefei, Li, Fengyuan, Gu, Zelin, Liu, Qi, He, Liqing, Shao, Tuo, Song, Qing, Zhu, Fenxia, Zhang, Lihua, Jiang, Mengwei, Zhou, Yun, Barve, Shirish, Zhang, Xiang, McClain, Craig J., Feng, Wenke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317518/
https://www.ncbi.nlm.nih.gov/pubmed/31571251
http://dx.doi.org/10.1002/hep.30975