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PyRod Enables Rational Homology Model‐based Virtual Screening Against MCHR1

Several encouraging pre‐clinical results highlight the melanin‐concentrating hormone receptor 1 (MCHR1) as promising target for anti‐obesity drug development. Currently however, experimentally resolved structures of MCHR1 are not available, which complicates rational drug design campaigns. In this s...

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Detalles Bibliográficos
Autores principales: Schaller, David, Wolber, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317519/
https://www.ncbi.nlm.nih.gov/pubmed/32329245
http://dx.doi.org/10.1002/minf.202000020