Cargando…

Obesity reduces mammary epithelial cell TGFβ1 activity through macrophage‐mediated extracellular matrix remodeling

Obesity is a risk factor for breast cancer in postmenopausal and high‐risk premenopausal women. Changes within the obese breast microenvironment may increase breast cancer risk. Transforming growth factor beta‐1 (TGFβ1) is a major regulator of mammary epithelial stem/progenitor cells, and its activi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chamberlin, Tamara, Thompson, Victoria, Hillers‐Ziemer, Lauren E., Walton, Brenna N., Arendt, Lisa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317547/ https://www.ncbi.nlm.nih.gov/pubmed/32359100 http://dx.doi.org/10.1096/fj.202000228RR

Ejemplares similares

Factors associated with obesity alter matrix remodeling in breast cancer tissues
por: Zhang, Yang, et al.
Publicado: (2020)

SAT-129 Interactions Between Macrophages and Cancer Stem-Like Cells Promote Mammary Tumor Angiogenesis Under Obesity
por: Hillers-Ziemer, Lauren, et al.
Publicado: (2020)

Obesity Promotes Cooperation of Cancer Stem-Like Cells and Macrophages to Enhance Mammary Tumor Angiogenesis
por: Hillers-Ziemer, Lauren E., et al.
Publicado: (2020)

Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity
por: Chamberlin, Tamara, et al.
Publicado: (2017)

Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion()()
por: Hillers, Lauren E., et al.
Publicado: (2018)

Obesity-Activated Lung Stromal Cells Promote Myeloid Lineage Cell Accumulation and Breast Cancer Metastasis
por: Hillers-Ziemer, Lauren E., et al.
Publicado: (2021)

Breast cancer microenvironment and obesity: challenges for therapy
por: Hillers-Ziemer, Lauren E., et al.
Publicado: (2022)

The extracellular matrix as an adhesion checkpoint for mammary epithelial function
por: Katz, Elad, et al.
Publicado: (2007)

Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes
por: Fata, Jimmie E, et al.
Publicado: (2004)

A muscle cell‐macrophage axis involving matrix metalloproteinase 14 facilitates extracellular matrix remodeling with mechanical loading
por: Peck, Bailey D., et al.
Publicado: (2022)

Regulation of functional cytodifferentiation and histogenesis in mammary epithelial cells: role of the extracellular matrix.
por: Bissell, M J, et al.
Publicado: (1989)

Regulation of mammary differentiation by the extracellular matrix.
por: Blum, J L, et al.
Publicado: (1989)

Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice
Publicado: (1995)

Extracellular matrix remodelling in COPD
por: Karakioulaki, Meropi, et al.
Publicado: (2020)

Stromal and epithelial TGF-β signaling in mammary tumorigenesis
por: Moses, HL, et al.
Publicado: (2005)

Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling
por: Gula, Grzegorz, et al.
Publicado: (2020)

Macrophage-extracellular matrix interactions: Perspectives for tissue engineered heart valve remodeling
por: Poulis, Nikolaos, et al.
Publicado: (2022)

The Effect of Mammary Extracellular Matrix in Controlling Oral and Mammary Cancer Cells
por: Pavuluri, Sivapriya, et al.
Publicado: (2018)

Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice
por: Wang, Ying, et al.
Publicado: (2020)

Transcriptome analysis of mammary epithelial cell gene expression reveals novel roles of the extracellular matrix
por: Wanyonyi, Stephen S., et al.
Publicado: (2017)

Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer‐Like Phenotype
por: Bahcecioglu, Gokhan, et al.
Publicado: (2021)

Mammary epithelial polarity and macrophage infiltration
por: Xu, Ren
Publicado: (2017)

Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution
por: Baiocchini, Andrea, et al.
Publicado: (2016)

Suppression of p53 function in normal human mammary epithelial cells increases sensitivity to extracellular matrix–induced apoptosis
por: Seewaldt, Victoria L., et al.
Publicado: (2001)

Extracellular Matrix Remodeling in Human Disease
por: Sonbol, Hala Salim
Publicado: (2018)

Extracellular Matrix Remodeling of Adipose Tissue in Obesity and Metabolic Diseases
por: Ruiz-Ojeda, Francisco Javier, et al.
Publicado: (2019)

Extracellular Vesicles and Matrix Remodeling Enzymes: The Emerging Roles in Extracellular Matrix Remodeling, Progression of Diseases and Tissue Repair
por: Nawaz, Muhammad, et al.
Publicado: (2018)

Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution
Publicado: (1992)

Human Breast Extracellular Matrix Microstructures and Protein Hydrogel 3D Cultures of Mammary Epithelial Cells
por: Keller, Chandler R., et al.
Publicado: (2021)

The Bladder Is a Novel Target of Developmental Polychlorinated Biphenyl Exposure Linked to Increased Inflammatory Cells in the Bladder of Young Mice
por: Kennedy, Conner L., et al.
Publicado: (2021)

Epithelial and extracellular matrix injury in quartz-inflamed lung: role of the alveolar macrophage.
por: Donaldson, K, et al.
Publicado: (1992)

Transitional Remodeling of the Hepatic Extracellular Matrix in Alcohol-Induced Liver Injury
por: Poole, Lauren G., et al.
Publicado: (2016)

The contribution of dynamic stromal remodeling during mammary development to breast carcinogenesis
por: McCready, Jessica, et al.
Publicado: (2010)

Apical and Basal Matrix Remodeling Control Epithelial Morphogenesis
por: Diaz-de-la-Loza, Maria-del-Carmen, et al.
Publicado: (2018)

Airway Epithelial Cell Migration Dynamics: Mmp-9 Role in Cell–Extracellular Matrix Remodeling
por: Legrand, Claire, et al.
Publicado: (1999)

Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition
por: Ruiz-Mitjana, Anna, et al.
Publicado: (2022)

Regulation of differentiation and polarized secretion in mammary epithelial cells maintained in culture: extracellular matrix and membrane polarity influences
Publicado: (1987)

Extracellular matrix promotes clathrin-dependent endocytosis of prolactin and STAT5 activation in differentiating mammary epithelial cells
por: Bridgewater, Rebecca E., et al.
Publicado: (2017)

Extracellular matrix remodelling properties of human fibrocytes
por: Bianchetti, Lorenza, et al.
Publicado: (2012)

Extracellular Matrix Remodeling During Palate Development
por: Wang, Xia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8jgfh8tdpepn4qkq7q5om4vl9o