The development and characterization of a long acting anti‐thrombotic von Willebrand factor (VWF) aptamer

BACKGROUND: Thrombus formation involves coagulation proteins and platelets. The latter, referred to as platelet‐mediated thrombogenesis, is predominant in arterial circulation. Platelet thrombogenesis follows vascular injury when extracellular von Willebrand factor (VWF) binds via its A3 domain to e...

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Detalles Bibliográficos
Autores principales: Zhu, Shuhao, Gilbert, James C., Hatala, Paul, Harvey, Warren, Liang, Zicai, Gao, Shan, Kang, Daiwu, Jilma, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
THROMBOSIS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317574/
https://www.ncbi.nlm.nih.gov/pubmed/32011054
http://dx.doi.org/10.1111/jth.14755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317574/
https://www.ncbi.nlm.nih.gov/pubmed/32011054
http://dx.doi.org/10.1111/jth.14755

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