COSMC mutations reduce T‐synthase activity in advanced Alzheimer's disease

INTRODUCTION: Mutations in brain tissues that cumulate with age may contribute to Alzheimer's disease (AD). Abnormal glycoprotein and Tn antigen expression have been demonstrated in AD. We identified C1GALT1C1/COSMC mutations in AD and age‐matched normals without AD. The COSMC coding mutations...

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Detalles Bibliográficos
Autores principales: Gollamudi, Seema, Lekhraj, Rukmani, Lalezari, Shirin, Lalezari, Parviz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317644/
https://www.ncbi.nlm.nih.gov/pubmed/32607408
http://dx.doi.org/10.1002/trc2.12040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317644/
https://www.ncbi.nlm.nih.gov/pubmed/32607408
http://dx.doi.org/10.1002/trc2.12040

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