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Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity

BACKGROUND: Emerging biomarkers from medical imaging or molecular characterization of tumour biopsies open up for combining the two and exploiting their synergy in treatment planning of cancer patients. We generated a paired data set of imaging- and gene-based hypoxia biomarkers in cervical cancer,...

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Detalles Bibliográficos
Autores principales: Fjeldbo, Christina S., Hompland, Tord, Hillestad, Tiril, Aarnes, Eva-Katrine, Günther, Clara-Cecilie, Kristensen, Gunnar B., Malinen, Eirik, Lyng, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317686/
https://www.ncbi.nlm.nih.gov/pubmed/32580139
http://dx.doi.org/10.1016/j.ebiom.2020.102841