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Involvement of the epidermal growth factor receptor in IL‐13–mediated corticosteroid‐resistant airway inflammation

BACKGROUND: Effective treatment for severe asthma is a significant unmet need. While eosinophilic inflammation caused by type 2 cytokines is responsive to corticosteroid and biologic therapies, many severe asthmatics exhibit corticosteroid‐unresponsive mixed granulocytic inflammation. OBJECTIVE: Her...

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Detalles Bibliográficos
Autores principales: Davies, Elizabeth R., Perotin, Jeanne‐Marie, Kelly, Joanne F.C., Djukanovic, Ratko, Davies, Donna E., Haitchi, Hans Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317751/
https://www.ncbi.nlm.nih.gov/pubmed/32096290
http://dx.doi.org/10.1111/cea.13591