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A Pronucleotide Probe for Live‐Cell Imaging of Protein AMPylation

Conjugation of proteins to AMP (AMPylation) is a prevalent post‐translational modification (PTM) in human cells, involved in the regulation of unfolded protein response and neural development. Here we present a tailored pronucleotide probe suitable for in situ imaging and chemical proteomics profili...

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Detalles Bibliográficos
Autores principales: Kielkowski, Pavel, Buchsbaum, Isabel Y., Becker, Tobias, Bach, Kathrin, Cappello, Silvia, Sieber, Stephan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317759/
https://www.ncbi.nlm.nih.gov/pubmed/32027064
http://dx.doi.org/10.1002/cbic.201900716