Unexpected NADPH Hydratase Activity in the Nitrile Reductase QueF from Escherichia coli

The nitrile reductase QueF catalyzes NADPH‐dependent reduction of the nitrile group of preQ(0) (7‐cyano‐7‐deazaguanine) into the primary amine of preQ(1) (7‐aminomethyl‐7‐deazaguanine), a biologically unique reaction important in bacterial nucleoside biosynthesis. Here we have discovered that the Qu...

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Detalles Bibliográficos
Autores principales: Jung, Jihye, Braun, Jan, Czabany, Tibor, Nidetzky, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317782/
https://www.ncbi.nlm.nih.gov/pubmed/31850614
http://dx.doi.org/10.1002/cbic.201900679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317782/
https://www.ncbi.nlm.nih.gov/pubmed/31850614
http://dx.doi.org/10.1002/cbic.201900679

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