Cargando…

Unexpected NADPH Hydratase Activity in the Nitrile Reductase QueF from Escherichia coli

The nitrile reductase QueF catalyzes NADPH‐dependent reduction of the nitrile group of preQ(0) (7‐cyano‐7‐deazaguanine) into the primary amine of preQ(1) (7‐aminomethyl‐7‐deazaguanine), a biologically unique reaction important in bacterial nucleoside biosynthesis. Here we have discovered that the Qu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jung, Jihye, Braun, Jan, Czabany, Tibor, Nidetzky, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317782/ https://www.ncbi.nlm.nih.gov/pubmed/31850614 http://dx.doi.org/10.1002/cbic.201900679

Ejemplares similares

QueF-Like, a Non-Homologous Archaeosine Synthase from the Crenarchaeota
por: Bon Ramos, Adriana, et al.
Publicado: (2017)

Strategy for successful expression of the Pseudomonas putida nitrile hydratase activator P14K in Escherichia coli
por: Liu, Yi, et al.
Publicado: (2013)

A Nitrile Hydratase in the Eukaryote Monosiga brevicollis
por: Foerstner, Konrad U., et al.
Publicado: (2008)

Protection of the Queuosine Biosynthesis Enzyme QueF from Irreversible Oxidation by a Conserved Intramolecular Disulfide
por: Mohammad, Adeba, et al.
Publicado: (2017)

Nitrile Hydratase Genes Are Present in Multiple Eukaryotic Supergroups
por: Marron, Alan O., et al.
Publicado: (2012)

Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase
por: Van Wyk, Jennifer C., et al.
Publicado: (2022)

Nitrile hydratase of Rhodococcus erythropolis: characterization of the enzyme and the use of whole cells for biotransformation of nitriles
por: Kamble, Ashwini L., et al.
Publicado: (2012)

Simultaneous purification of nitrile hydratase and amidase of Alcaligenes sp. MTCC 10674
por: Bhatia, S. K., et al.
Publicado: (2013)

Recent Advances and Promises in Nitrile Hydratase: From Mechanism to Industrial Applications
por: Cheng, Zhongyi, et al.
Publicado: (2020)

The Alpha Subunit of Nitrile Hydratase Is Sufficient for Catalytic Activity and Post-Translational Modification
por: Nelp, Micah T., et al.
Publicado: (2014)

Self-Subunit Swapping Occurs in Another Gene Type of Cobalt Nitrile Hydratase
por: Liu, Yi, et al.
Publicado: (2012)

A high-throughput screening assay for distinguishing nitrile hydratases from nitrilases
por: Angelini, Leticia Mara Lima, et al.
Publicado: (2015)

Functional Expression and Characterization of a Panel of Cobalt and Iron-Dependent Nitrile Hydratases
por: Grill, Birgit, et al.
Publicado: (2020)

Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis
por: Ma, Dong, et al.
Publicado: (2022)

Purification and characterization of nitrile hydratase of mutant 4D of Rhodococcus rhodochrous PA-34
por: Pratush, Amit, et al.
Publicado: (2012)

The Active Site Sulfenic Acid Ligand in Nitrile Hydratases Can Function as a Nucleophile
por: Martinez, Salette, et al.
Publicado: (2014)

An Aeroplysinin-1 Specific Nitrile Hydratase Isolated from the Marine Sponge Aplysina cavernicola
por: Lipowicz, Bartosz, et al.
Publicado: (2013)

Overexpression and characterization of two types of nitrile hydratases from Rhodococcus rhodochrous J1
por: Lan, Yao, et al.
Publicado: (2017)

Computational Design of Nitrile Hydratase from Pseudonocardia thermophila JCM3095 for Improved Thermostability
por: Cheng, Zhongyi, et al.
Publicado: (2020)

Substrate Profiling of the Cobalt Nitrile Hydratase from Rhodococcus rhodochrous ATCC BAA 870
por: Mashweu, Adelaide R., et al.
Publicado: (2020)

Biodegradation of flonicamid by Ensifer adhaerens CGMCC 6315 and enzymatic characterization of the nitrile hydratases involved
por: Zhao, Yun-Xiu, et al.
Publicado: (2021)

Whole-cell bioreduction of aromatic α-keto esters using Candida tenuis xylose reductase and Candida boidinii formate dehydrogenase co-expressed in Escherichia coli
por: Kratzer, Regina, et al.
Publicado: (2008)

Construction of a subunit-fusion nitrile hydratase and discovery of an innovative metal ion transfer pattern
por: Xia, Yuanyuan, et al.
Publicado: (2016)

Spectroscopic and computational studies of nitrile hydratase: insights into geometric and electronic structure and the mechanism of amide synthesis
por: Light, Kenneth M., et al.
Publicado: (2015)

Maturation Mechanism of Nitrile Hydratase From Streptomyces canus CGMCC 13662 and Its Structural Character
por: Guo, Ling, et al.
Publicado: (2020)

A simple, efficient and rapid screening technique for differentiating nitrile hydratase and nitrilase producing bacteria
por: Sahu, Ruchi, et al.
Publicado: (2019)

Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family
por: Haft, Daniel H, et al.
Publicado: (2010)

Successful expression of the Bordetella petrii nitrile hydratase activator P14K and the unnecessary role of Ser115
por: Sun, Weifeng, et al.
Publicado: (2016)

BdcA, a Protein Important for Escherichia coli Biofilm Dispersal, Is a Short-Chain Dehydrogenase/Reductase that Binds Specifically to NADPH
por: Lord, Dana M., et al.
Publicado: (2014)

Response surface methodology: An effective optimization strategy for enhanced production of nitrile hydratase (NHase) by Rhodococcus rhodochrous (RS-6)
por: Sahu, Ruchi, et al.
Publicado: (2020)

Biodegradation potential of cyano-based ionic liquid anions in a culture of Cupriavidus spp. and their in vitro enzymatic hydrolysis by nitrile hydratase
por: Neumann, Jennifer, et al.
Publicado: (2013)

Enzymatic Redox Cascade for One-Pot Synthesis of Uridine 5′-Diphosphate Xylose from Uridine 5′-Diphosphate Glucose
por: Eixelsberger, Thomas, et al.
Publicado: (2014)

High Regioselectivity Production of 5-Cyanovaleramide from Adiponitrile by a Novel Nitrile Hydratase Derived from Rhodococcus erythropolis CCM2595
por: Wang, Li, et al.
Publicado: (2020)

Development of variously functionalized nitrile oxides
por: Asahara, Haruyasu, et al.
Publicado: (2015)

Soft Scorpionate Hydridotris(2‐mercapto‐1‐methylimidazolyl) borate) Tungsten‐Oxido and ‐Sulfido Complexes as Acetylene Hydratase Models
por: Vidovič, Carina, et al.
Publicado: (2020)

Efficient Overproduction of Active Nitrile Hydratase by Coupling Expression Induction and Enzyme Maturation via Programming a Controllable Cobalt-Responsive Gene Circuit
por: Han, Laichuang, et al.
Publicado: (2020)

Biofilm Modifies Expression of Ribonucleotide Reductase Genes in Escherichia coli
por: Cendra, Maria del Mar, et al.
Publicado: (2012)

NADPH‐related processes studied with a SoxR‐based biosensor in Escherichia coli
por: Spielmann, Alina, et al.
Publicado: (2018)

Change in Cofactor Specificity of Oxidoreductases by Adaptive Evolution of an Escherichia coli NADPH-Auxotrophic Strain
por: Bouzon, Madeleine, et al.
Publicado: (2021)

d-Xylulose kinase from Saccharomyces cerevisiae: Isolation and characterization of the highly unstable enzyme, recombinantly produced in Escherichia coli
por: Pival, Simone L., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ujtqa0b43bjje6n5eoct8i644t