Cargando…
Unexpected NADPH Hydratase Activity in the Nitrile Reductase QueF from Escherichia coli
The nitrile reductase QueF catalyzes NADPH‐dependent reduction of the nitrile group of preQ(0) (7‐cyano‐7‐deazaguanine) into the primary amine of preQ(1) (7‐aminomethyl‐7‐deazaguanine), a biologically unique reaction important in bacterial nucleoside biosynthesis. Here we have discovered that the Qu...
Autores principales: | Jung, Jihye, Braun, Jan, Czabany, Tibor, Nidetzky, Bernd |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317782/ https://www.ncbi.nlm.nih.gov/pubmed/31850614 http://dx.doi.org/10.1002/cbic.201900679 |
Ejemplares similares
-
QueF-Like, a Non-Homologous Archaeosine Synthase from the Crenarchaeota
por: Bon Ramos, Adriana, et al.
Publicado: (2017) -
Strategy for successful expression of the Pseudomonas putida nitrile hydratase activator P14K in Escherichia coli
por: Liu, Yi, et al.
Publicado: (2013) -
A Nitrile Hydratase in the Eukaryote Monosiga brevicollis
por: Foerstner, Konrad U., et al.
Publicado: (2008) -
Protection of the Queuosine Biosynthesis Enzyme QueF from Irreversible Oxidation by a Conserved Intramolecular Disulfide
por: Mohammad, Adeba, et al.
Publicado: (2017) -
Nitrile Hydratase Genes Are Present in Multiple Eukaryotic Supergroups
por: Marron, Alan O., et al.
Publicado: (2012)