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A novel assay for studying the involvement of blood cells in whole blood thrombin generation

BACKGROUND: Fluorogenic thrombin generation (TG) assays are commonly used to determine global coagulation phenotype in plasma. Whole blood (WB)‐TG assays reach one step closer to physiology by involving the intrinsic blood cells, but erythrocytes cause variable quenching of the fluorescence signals,...

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Detalles Bibliográficos
Autores principales: Wan, Jun, Konings, Joke, Yan, Qiuting, Kelchtermans, Hilde, Kremers, Romy, de Laat, Bas, Roest, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317846/
https://www.ncbi.nlm.nih.gov/pubmed/32108990
http://dx.doi.org/10.1111/jth.14786