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Size‐dependent secretory protein reflux into the cytosol in association with acute endoplasmic reticulum stress
Once secretory proteins have been targeted to the endoplasmic reticulum (ER) lumen, the proteins typically remain partitioned from the cytosol. If the secretory proteins misfold, they can be unfolded and retrotranslocated into the cytosol for destruction by the proteasome by ER‐Associated protein De...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons A/S
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317852/ https://www.ncbi.nlm.nih.gov/pubmed/32246734 http://dx.doi.org/10.1111/tra.12729 |