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Unravelling the heterogeneity and dynamic relationships of tumor‐infiltrating T cells by single‐cell RNA sequencing analysis

T cells are crucial for the success of immune‐based cancer therapy. Reinvigorating antitumor T cell activity by blocking checkpoint inhibitory receptors has provided clinical benefits for many cancer patients. However, the efficacy of these treatments varies in cancer patients and the mechanisms und...

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Detalles Bibliográficos
Autores principales: Yu, Xin, Zhang, Lei, Chaudhry, Ashutosh, Rapaport, Aaron S., Ouyang, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317876/
https://www.ncbi.nlm.nih.gov/pubmed/32272497
http://dx.doi.org/10.1002/JLB.6MR0320-234R