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Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections

Elimination of pulmonary Pseudomonas aeruginosa (PA) infections is challenging to accomplish with antibiotic therapies, mainly due to resistance mechanisms. Quorum sensing inhibitors (QSIs) interfering with biofilm formation can thus complement antibiotics. For simultaneous and improved delivery of...

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Detalles Bibliográficos
Autores principales: Ho, Duy‐Khiet, Murgia, Xabier, De Rossi, Chiara, Christmann, Rebekka, Hüfner de Mello Martins, Antonio G., Koch, Marcus, Andreas, Anastasia, Herrmann, Jennifer, Müller, Rolf, Empting, Martin, Hartmann, Rolf W., Desmaele, Didier, Loretz, Brigitta, Couvreur, Patrick, Lehr, Claus‐Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317969/
https://www.ncbi.nlm.nih.gov/pubmed/32243047
http://dx.doi.org/10.1002/anie.202001407