Transaldolase haploinsufficiency in subjects with acetaminophen‐induced liver failure

Transaldolase (TAL) is an enzyme in the pentose phosphate pathway (PPP) that generates NADPH for protection against oxidative stress. While deficiency of other PPP enzymes, such as transketolase (TKT), are incompatible with mammalian cell survival, mice lacking TAL are viable and develop progressive...

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Detalles Bibliográficos
Autores principales: Oaks, Zachary, Jimah, John, Grossman, Craig C., Beckford, Miguel, Kelly, Ryan, Banerjee, Sanjay, Niland, Brian, Miklossy, Gabriella, Kuloglu, Zarife, Kansu, Aydan, Lee, William, Szonyi, Laszlo, Banki, Katalin, Perl, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317976/
https://www.ncbi.nlm.nih.gov/pubmed/31769880
http://dx.doi.org/10.1002/jimd.12197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317976/
https://www.ncbi.nlm.nih.gov/pubmed/31769880
http://dx.doi.org/10.1002/jimd.12197

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